Cannabinoids | Terpenes | Conditions | Effects

Cannabinoids are naturally occurring molecules found in cannabis that are linked to a number of medical benefits and treatments. The Cannabis Review | Cannabinoids is a collection of scientific studies that identifies the conditions cannabinoids treat, by what mechanism, and the magnitude of the effect.

Grade

This is the measurement of the nature and methodology of the scientific study.

Double-blind, placebo controlled clinical study
Open clinical trial study; no control group and no blinded clinical trial
Non-human subject research on isolated cannabis compounds
Non-human subject research on cannabis compound in a mixture

Magnitude of Effect

This identifies how effective the biological activity of the cannabinoid was treating the
condition.

major Biological activity has a major effect on the condition
moderate Biological activity has a moderate effect on the condition
minor Biological activity has a minor effect on the condition

Primary Studies

The following are scientific studies that have shown the effectiveness of cannabinoids treating specific conditions.
Study names are linked to the studies, click to view.

Cannabinoid Condition treated Effect Amount used Study Grade
CBC
(Cannabichromene)
Colitis Antiinflammatory(major) NA The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis
Depression Antidepressant(major) 20mg/kg,
40mg/kg,
80mg/kg

Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L
Edema Antiinflammatory(major) NA
Anti-inflammatory properties of cannabichromene

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Inflammation-induced hypermotility Antiinflammatory(major) 10mg/kg
Inhibitory effect of cannabichromene, a non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice
Microbiological Contamination Antimicrobial(major) NA
Biological Activity of Cannabichromene, its Homologs and Isomers

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CBD
(Cannabidiol)
Acute lung injury Antiinflammatory(moderate) 20mg/kg
Cannabidiol, a non-psychotropic plant-derived cannabinoid, decreases inflammation in a murine model of acute lung injury: Role for the adenosine A2A receptor
Acute Pancreatitis Antiinflammatory(major) 0.5mg/kg
Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice
AD-related neuroinflammation Antiinflammatory(major) 2.5 or 10mg/kg
Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression
Alzheimer’s Disease Neuroprotectant(moderate) NA
The marijuana component cannabidiol inhibits β-amyloid-induced tau protein hyperphosphorylation through Wnt/β-catenin pathway rescue in PC12 cells
Anorexia Appetite Stimulant(major) NA
Effects of Dronabinol on Anorexia and disturbed behavior in patients with Alzheimer’s Disease

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Anxiety Anxiolytic(major) 600mg
Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients

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Appetite Loss Appetite Stimulant(moderate) NA
Cannabidiol attenuates the appetitive effects of Delta 9-tetrahydrocannabinol in humans smoking their chosen cannabis
Arthritis Antiarthritic(major) 5mg/kg,
25mg/kg

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.
Bacterial Contamination Antibacterial(moderate) 50μg/ml
Antibacterial activity of Δ9-tetrahydrocannabinol and cannabidiol

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Brain Injury Neuroprotectant(major) 300mg
Comparison of Cannabidiol, Antioxidants, and Diuretics in Reversing Binge Ethanol-Induced Neurotoxicity

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Breathing Difficulties Antidyspnoea(moderate) 10mg
Cannabinoid effects on ventilation and breathlessness: A pilot study of efficacy and safety
Cancer Anticancer(major) NA
The Combination of Cannabidiol and Δ9-Tetrahydrocannabinol Enhances the Anticancer Effects of Radiation in an Orthotopic Murine Glioma Model

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Antitumor(major) NA
Antitumor Activity of Plant Cannabinoids with Emphasis on the Effect of Cannabidiol on Human Breast Carcinoma

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Cancer Antiproliferative(moderate) 1–10µM
Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: pro-apoptotic effects and underlying mechanisms

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Cardiovascular Complications Cardiac Proctection(major) NA
Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy
Central Neuropathic Pain Analgesic(moderate) 25mg/mL
Oromucosal Δ9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: An uncontrolled, open-label, 2-year extension trial
Chronic Pain Antiinflammatory(minor) 2.5–20mg/kg,
20mg/kg

The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain
Depression Antidepressant(moderate) 15mg/kg,
30mg/kg,
45mg/kg

Prohedonic Effect of Cannabidiol in a Rat Model of Depression

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Diabetes Antidiabetic(moderate) 100mg
Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study
Diabetic Complications Antiinflammatory(major) NA
Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption

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Dystonia Antidystonic(moderate) 100 to 600mg
Open label evaluation of cannabidiol in dystonic movement disorders
200mg
Cannabidiol in dystonic movement disorders
Epilepsy Antiepileptic(moderate) 200-300mg
Chronic administration of cannabidiol to healthy volunteers and epileptic patients

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Epilepsy Anticonvulsant(major) 1mg/kg,
10mg/kg,
100mg/kg

Cannabidiol exerts anti-convulsant effects in animal models of temporal lobe and partial seizures

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Facial Emotion Recognition Improves recognition of emotional facial(moderate) 16mg
Acute effects of delta-9-tetrahydrocannabinol, cannabidiol and their combination on facial emotion recognition: a randomised, double-blind, placebo-controlled study in cannabis users
Glaucoma Antiglaucoma(minor) 20mg,
40mg

Effect of Sublingual Application of Cannabinoids on Intraocular Pressure: A Pilot Study
Glioblastoma multiforme Anticancer(major) NA
A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma
Huntington’s Disease Neuroprotective(moderate) 10mg/kg
Controlled clincal trial of cannabidiol in Huntington’s disease
Hyperlocomotion Antipsychotic(moderate) 15–60mg/kg
Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice
Immobility Antidepressant(moderate) 10–60nmol
Antidepressant-like effect of cannabidiol injection into the ventral medial prefrontal cortex—Possible involvement of 5-HT1A and CB1 receptors
Immune System related diseases Auto-immunity(moderate) 2.5 or 5mg/kg
Cannabidiol-induced Lymphopenia does not involve NKT and NK Cells
Inflammation Antiinflammatory(moderate) 5–40mg/kg
Oral anti-inflammatory activity of cannabidiol, a non-psychoactive constituent of cannabis, in acute carrageenan-induced inflammation in the rat paw
Insomnia Improve Sleep(moderate) 25mg,
6mg to 12mg

Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report
Multiple sclerosis Analgesic(moderate) 2-10inhalations
A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis

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Antinociceptive(moderate) NA
Cannabinoid-induced effects on the nociceptive system: a neurophysiological study in patients with secondary progressive multiple sclerosis
Antispasticity(moderate) NA
Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis

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Neuroprotection(moderate) 2.5–120mg
A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms
Urinary Protection(moderate) 2.5mg
An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis
Nausea Antiemetic(moderate) 200mg/kg
Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT1A somatodendritic autoreceptors in the dorsal raphe nucleus

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Neuroinflammatory diseases Antiinflammatory(minor) NA
Anti-inflammatory effects of the cannabidiol derivative dimethylheptyl-cannabidiol – studies in BV-2 microglia and encephalitogenic T cells
Osteoporosis Bone Stimulant(moderate) NA
Regulation of bone by cannabinoid and cannabinoid-like receptors
Pain Analgesic(moderate) NA
An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics

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Parkinson’s Disease Neuroprotectant(moderate) 300mg
Effects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial

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Antidystonic and Parkinsonism-aggravating(moderate) 300mg
Open label evaluation of cannabidiol in dystonic movement disorders
Pathological memory T cells and in Autoimmune diseases Antiinflammatory(major) NA
Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells
Peripheral pain response Analgesic(moderate) NA
(+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only
Posttraumatic stress disorder Anxiolytic(moderate) 32mg
Cannabidiol enhances consolidation of explicit fear extinction in humans

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Psychotic Experiences Antipsychotic(minor) NA
Cannabis with high cannabidiol content is associated with fewer psychotic experiences
Retinal Inflammatory Antiinflammatory(moderate) NA
Mediation of Cannabidiol Anti-inflammation in the Retina by Equilibrative Nucleoside Transporter and A2A Adenosine Receptor
Rheumatic Diseases Antiinflammatory(moderate) NA
Cannabidiol—transdermal delivery and anti-inflammatory effect in a murine model
Schizophrenia Antipsychotic(moderate) 0.3μM,
1μM,
3μM,
10μM,
30μM

Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
Sepsis Antiinflammatory(minor) NA
Effect of cannabidiol on sepsis-induced motility disturbances in mice: involvement of CB1 receptors and fatty acid amide hydrolase
Spasticity Antispasticity(minor) NA
Randomized controlled trial of cannabis-based medicine in spasticity caused by multiple sclerosis
Spinal Injury Neuroprotectant(moderate) 20mg/kg
Cannabidiol-treated Rats Exhibited Higher Motor Score After Cryogenic Spinal Cord Injury
Uveitis Antiinflammatory(major) 5mg/kg
Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation
CBDA
(Cannabidiolic acid)
Cancer Anticancer(moderate) NA
Cannabidiolic acid, a (major) cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration
Inflammation Antiinflammatory(minor) 2μM
Cannabidiolic Acid as a Selective Cyclooxygenase-2 Inhibitory Component in Cannabis
Nausea Antiemetic(moderate) 0.5mg/kg
Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation

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CBDV
(Cannabidivarin)
Epilepsy Anticonvulsant(moderate) NA
Cannabis in epilepsy: From clinical practice to basic research focusing on the possible role of cannabidivarin

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CBG
(Cannabigerol)
Cancer Antitumor(major) N/A
Boron trifluoride etherate on silica-A modified lewis acid reagent (VII). Antitumor activity of cannabigerol against human oral epitheloid carcinoma cells

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Glaucoma Antiglaucoma(moderate) NA
A Comparison of the Ocular and Central Effects of Δ9-Tetrahydrocannabinol and Cannabigerol
Human immune diseases Immunosuppressive(moderate) NA
A Cannabigerol Derivative Suppresses Immune Responses and Protects Mice from Experimental Autoimmune Encephalomyelitis
Huntington’s Disease Neuroprotectant(moderate) NA
Neuroprotective Properties of Cannabigerol in Huntington’s Disease: Studies in R6/2 Mice and 3-Nitropropionate-lesioned Mice

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Irritable bowel syndrome Antiinflammatory(major) NA
Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease
MRSA Antibacterial(moderate) NA
Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study
Neuroinflammation Antiinflammatory(moderate) NA
A Cannabigerol Quinone Alleviates Neuroinflammation in a Chronic Model of Multiple Sclerosis
Oxidative-stress related disorders Antioxidant(moderate) NA
Cannabinoid CB2 receptors are involved in the protection of RAW264.7 macrophages against the oxidative stress: an in vitro study
CBGA
(Cannabigerolic Acid)
Inflammation Antiinflammatory(moderate) NA
Evaluation of the Cyclooxygenase Inhibiting Effects of Six Major Cannabinoids Isolated from Cannabis sativa.
CBN
(Cannabinol)
ALS Neuroprotectant(moderate) 5mg/kg Cannabinol delays symptom onset in SOD1 (G93A) transgenic mice without affecting survival
Low feeding behaviour Appetite Stimulant(minor) NA Cannabinol and cannabidiol exert opposing effects on rat feeding patterns
MRSA Antibacterial(moderate) NA Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study
Pain Analgesic(major) NA Comparative analgesic activity of various naturally occurring cannabinoids in mice and rats
Tonic-clonic seizure Anticonvulsant(moderate) NA Anticonvulsant properties of Δ9-tetrahydrocannabinol and other cannabinoids
Tumor Antitumor(moderate) 100mg/kg,
200mg/kg,
50mg/kg
Antineoplastic Activity of Cannabinoids
THC
(Tetrahydrocannabinol)
Acute psychosocial stress Anxiolytic(moderate) 7.5mg,
12.5mg
Dose-related effects of delta-9-THC on emotional responses to acute psychosocial stress
ADHD Improves behaviour(moderate) 71ng/mL Cannabis improves symptoms of ADHD
ADHD Neuroprotectant(moderate) NA Oral Δ9-Tetrahydrocannabinol Improved Refractory Gilles de la Tourette Syndrome in an Adolescent by Increasing Intracortical Inhibition: A Case Report
ALS Neuroprotectant(moderate) NA The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset
Alzheimer’s Disease Neuroprotectant(major) NA The potential therapeutic effects of THC on Alzheimer’s disease

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Anorexia Appetite Stimulant(moderate) 2.5mg A phase II study of delta-9-tetrahydrocannabinol for appetite stimulation in cancer-associated anorexia

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Anxiety Anxiolytic(moderate) NA A double-blind trial of delta 9-tetrahydrocannabinol in primary anorexia nervosa

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Asthma Bronchodilating activity(moderate) 200mg Bronchodilator effect of delta1-tetrahydrocannabinol administered by aerosol of asthmatic patients

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Breathing Difficulties Bronchodilating activity(moderate) 20mg Acute and subacute bronchial effects of oral cannabinoids
Chemosensory alterations Appetite Stimulant(major) 2.5mg
Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial
Crohn’s Disease Antiinflammatory(minor) 115mg Cannabis induces a clinical response in patients with Crohn’s disease: a prospective placebo-controlled study
Dementia Neuroprotective(moderate) 3mg
Effects of tetrahydrocannabinol on balance and gait in patients with dementia: A randomised controlled crossover trial
Edema Antiinflammatory(minor) NA Antipyretic, analgesic and anti-inflammatory effects of Δ9-tetrahydrocannabinol in the rat
Emetic Antiemetic(major) 5mg,
10mg,
15mg
Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications

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Glioblastoma multiforme Anticaner(major) NA A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma
Antitumor(moderate) NA
A pilot clinical study of Delta(9)-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme
Glaucoma Antiglaucoma(moderate) 2.8% of mixture
Effects of tetrahydrocannabinol on arterial and intraocular hypertension

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HIV-infected Appetite Stimulant(moderate) NA
A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men
Immobility Antidepressant(moderate) 2.5mg/kg Antidepressant-like effect of Δ9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L
Intestinal inflammation Antiinflammatory(moderate) NA Chronic Administration of Δ9-Tetrahydrocannabinol Induces Intestinal Anti-Inflammatory MicroRNA Expression during Acute Simian Immunodeficiency Virus Infection of Rhesus Macaques
Friend leukemia virus-induced splenomegaly Antileukemic(major) 200mg/kg Antineoplastic Activity of Cannabinoids
Multiple Sclerosis Analgesic(moderate) 10mg A double-blind, randomized, placebo-controlled, parallel-group study of THC/CBD oromucosal spray in combination with the existing treatment regimen, in the relief of central neuropathic pain in patients with multiple sclerosis

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Antiemetic(moderate) 15mg/m2 Efficacy of tetrahydrocannabinol in patients refractory to standard antiemetic therapy.Efficacy, safety and tolerability of an orally administered cannabis extract in the treatment of spasticity in patients with multiple sclerosis: a randomized, double-blind, placebo-controlled, crossover study
Antispasticity(moderate) 33% of mixture The effect of cannabis on urge incontinence in patients with multiple sclerosis: a multicentre, randomised placebo-controlled trial (CAMS-LUTS)

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Antinociceptive(moderate) NA Cannabinoid-induced effects on the nociceptive system: a neurophysiological study in patients with secondary progressive multiple sclerosis
Urinary Protection(moderate) 2.5mg An open-label pilot study of cannabis-based extracts for bladder dysfunction in advanced multiple sclerosis
Improve neurogenic symptoms(moderate) 2.5–120mg A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms
Antitremor(moderate) NA Tetrahydrocannabinol for tremor in multiple sclerosis
Neurological disorders Neuroprotectant(moderate) NA Cannabidiol and (−)Δ9-tetrahydrocannabinol are neuroprotective antioxidants
Neuropathic Pain Analgesic(major) 25mg Smoked cannabis for chronic neuropathic pain: a randomized controlled trial
Nausea Antiemetic(moderate) 8.4mg,
16.9mg
Antiemetic efficacy of smoked marijuana: subjective and behavioral effects on nausea induced by syrup of ipecac

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Oxidative Stress Neuroprotectant(moderate) NA Reactive oxygen species and p38 phosphorylation regulate the protective effect of Δ9-tetrahydrocannabinol in the apoptotic response to NMDA
Antioxidant(minor) NA Understanding the Molecular Aspects of Tetrahydrocannabinol and Cannabidiol as Antioxidants
Pain Analgesic(minor) NA An open-label extension study to investigate the long-term safety and tolerability of THC/CBD oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics

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Antinociceptive(moderate) 1mg/kg,
5mg/kg
Dopamine D2 receptor antagonists prevent Δ9-tetrahydrocannabinol-induced antinociception in rats

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Posttraumatic stress disorder Antidepressant(moderate) 5mg Preliminary, open-label, pilot study of add-on oral Δ9-tetrahydrocannabinol in chronic post-traumatic stress disorder
Anxiolytic(moderate) NA Cannabinoid facilitation of fear extinction memory recall in humans
Schizophrenia Antipsychotic
(moderate)
2.5mg,
5mg

Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction
Spasticity Antispacity(moderate) 10 or 5mg Treatment of human spasticity with delta 9-tetrahydrocannabinol

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Sleep Apnea Improves sleep(moderate) 20mg Around-the-clock oral THC effects on sleep in male chronic daily cannabis smokers
Tourette’s Syndrome Antispacity(moderate) 10mg Delta 9-tetrahydrocannabinol (THC) is effective in the treatment of tics in Tourette syndrome: a 6-week randomized trial

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Transient lower oesophageal sphincter relaxations Antigastroesophageal reflux(moderate) 20mg
Effect of Delta(9)-tetrahydrocannabinol, a cannabinoid receptor agonist, on the triggering of transient lower oesophageal sphincter relaxations in dogs and humans
Traumatic Brain Injury Neuroprotective(moderate) NA
Effect of marijuana use on outcomes in traumatic brain injury
Vomiting Antiemetic(moderate) NA
Tetrahydrocannabinol vs. prochlorperazine. The effects of two antiemetics on patients undergoing radiotherapy
THCA
(Tetrahydrocannabinolic Acid)
Neurodegeneration Neuroprotective(moderate) 10μM Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP+ affected murine mesencephalic cultures
THCV
(Tetrahydrocannabivarin)
Acne Anti-acne(major) NA Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment
Diabetes Antidiabetic
(moderate)
5mg
Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study
Epelipsy Anticonvulsant(moderate) 0.25mg/kg Δ9-Tetrahydrocannabivarin suppresses in vitro epileptiform and in vivo seizure activity in adult rats
Ischaemia-reperfusion Antiinflammation(moderate) NA Δ8-Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors
Nausea Antinausea(minor) 10mg/kg Evaluation of the potential of the phytocannabinoids, cannabidivarin (CBDV) and Δ9-tetrahydrocannabivarin (THCV), to produce CB1 receptor inverse agonism symptoms of nausea in rats
Obesity Antiobesity(moderate) NA Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients.

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Stimulates neural effects(moderate) 10mg Neural Effects of Cannabinoid CB1 Neutral Antagonist Tetrahydrocannabivarin on Food Reward and Aversion in Healthy Volunteers

Secondary Materials

The following are study reviews and other materials of note

Cannabinoid Condition Treated Effect Study
CBC
(Cannabichromene)
Depression Antidepressant
minor
Review Article: Sleep, Pain and Cannabis
Epilepsy Antiepileptic
moderate
Marijuana Compounds: A Non-Conventional Therapeutic Approach to Epilepsy in Children
CBD
(Cannabidiol)
Bone diseases Stimulate Bone growth
moderate
Edible Marijuana: A New Frontier in the Culinary World
Cancer Anticancer
moderate
Cannabidiol as potential anticancer drug
Chronic Diseases Cerebroprotective
minor
Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke
Hypertension Antihypertension
moderate
Is the cardiovascular system a therapeutic target for cannabidiol?
Intestinal prokinetic Antiprokinetic
moderate
Edible Marijuana: A New Frontier in the Culinary World
Neurodegenerative Disorders Neuroprotective
major
Cannabidiol for neurodegenerative disorders: Important new clinical applications for this phytocannabinoid?
Psoriasis Antipsoriatic
moderate
Edible Marijuana: A New Frontier in the Culinary World
Schizophrenia Antipsychosis
moderate
A Critical Review of the Antipsychotic Effects of Cannabidiol: 30 Years of a Translational Investigation
Spasticity Antispasticity
minor
Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review
CBG
(Cannabigerol)
Breast cancer Antiproliferative
moderate
The system and cancer: Therapeutic implication
CBN
(Cannabinol)
ALS Neuroprotective
moderate
Can cannabinoids be a potential therapeutic tool in amyotrophic lateral sclerosis?
Bone Diseases Stimulate Bone Growth
minor
Role of cannabinoids in the regulation of bone remodeling
Glaucoma Antiglaucoma
moderate
Cannabinoids and glaucoma
Osteoporosis Stimulate Bone Growth
minor
Role of cannabinoids in the regulation of bone remodeling
THC
(Tetrahydrocannabinol)
Anorexia Stimulate appetite
moderate
The cancer cachexia syndrome
Bipolar Neuroprotective
moderate
Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential
Bone Diseases Stimulate Bone Growth
moderate
Role of cannabinoids in the regulation of bone remodeling
Crohn’s disease Antiinflammatory
major
Cannabis Finds Its Way into Treatment of Crohn’s Disease
Migraine Neuroprotective
minor
Cannabis for migraine treatment: the once and future prescription? An historical and scientific review
Osteoporosis Stimulate Bone Growth
minor
Role of cannabinoids in the regulation of bone remodeling
Spasm and pain Antispasmodic
moderate
Prescribing Cannabinoids for Multiple Sclerosis
THCV
(Tetrahydrocannabivarin)
Bone Diseases Bone Stimulant
moderate
Role of cannabinoids in the regulation of bone remodeling
Pain Analgesic
moderate
Are cannabidiol and Δ9-tetrahydrocannabivarin negative modulators of the system? A systematic review